Price comparison · Compounded GLP-1 medications

Compounded GLP-1 prices: semaglutide vs tirzepatide

The lowest listed cost for the first 12 weeks at each dose level, all-in, across the telehealth providers we cover.

· Prices checked

As of October 6, 2026, the lowest listed all-in cost for the first 12 weeks of a compounded GLP-1 at a starting dose, among the telehealth providers Inside Telehealth covers, is $298 for semaglutide (OrderlyMeds, 2-month starter, new customers only, estimate) and $477 for tirzepatide (Mochi Health, 3-month prepaid membership, estimate). With one all-inclusive fee (no separate membership), the lowest starting-dose figures are $298 for semaglutide (OrderlyMeds, estimate) and $507 for tirzepatide (Gentle Health, estimate). Totals include every required membership, medication and program charge.

Lowest 12-week cost by dose and plan type

The same five measures as each medication's full comparison, side by side. Each cell is the lowest listed all-in cost for the first 12 weeks among plans that meet that row's rule at that dose level. Doses differ between the two medications and between providers.

  • Monthly plans count three monthly charges at the same dose. That is a cash-flow assumption, not a verified 84-day supply, so those figures are marked Estimate.
  • A plan that must be prepaid for longer than 12 weeks shows its full upfront payment and is marked Prepaid in full.
  • Sales tax shown only at checkout is not included; Gentle Health states it adds no tax. Promotional prices are excluded.
  • Henry Meds states supply limits rather than weekly doses, so it is not placed in a dose level; see the semaglutide comparison under All doses.

Starting dose

MeasureSemaglutideup to 0.5 mg a weekTirzepatideup to 5 mg a week
Lowest with no commitmentmonth-to-month plansMochi Health$417EstimateMonthly membershipMochi Health$507EstimateMonthly membership
Lowest with a minimum termplans with a minimum number of months, billed monthlyGentle Health$405EstimateMonthly planOnly covered provider with this kind of plan at this dose.Gentle Health$507EstimateMonthly planOnly covered provider with this kind of plan at this dose.
Lowest if you prepayprepaid plansOrderlyMeds$298EstimateNew customers only2-month starter (new customers)Mochi Health$477EstimatePrepaid in full3-month prepaid membership (membership covers 3 months)
Lowest with one all-inclusive feeone fee covers medication, care and shipping; no separate membershipOrderlyMeds$298EstimateNew customers only2-month starter (new customers)Gentle Health$507EstimateMonthly plan
Lowest of any plan typeall plansOrderlyMeds$298EstimateNew customers only2-month starter (new customers)Mochi Health$477EstimatePrepaid in full3-month prepaid membership (membership covers 3 months)

Mid dose

MeasureSemaglutideabove 0.5 to 1.7 mg a weekTirzepatideabove 5 to 10 mg a week
Lowest with no commitmentmonth-to-month plansOrderlyMeds$447EstimateMonthly, pay per refillMochi Health$669EstimateMonthly membership
Lowest with a minimum termplans with a minimum number of months, billed monthlyGentle Health$477EstimateMonthly planOnly covered provider with this kind of plan at this dose.Gentle Health$657EstimateMonthly planOnly covered provider with this kind of plan at this dose.
Lowest if you prepayprepaid plansOrderlyMeds$373EstimateNew customers only2-month transfer (new customers)Mochi Health$639EstimatePrepaid in full3-month prepaid membership (membership covers 3 months)
Lowest with one all-inclusive feeone fee covers medication, care and shipping; no separate membershipOrderlyMeds$373EstimateNew customers only2-month transfer (new customers)Gentle Health$657EstimateMonthly plan
Lowest of any plan typeall plansOrderlyMeds$373EstimateNew customers only2-month transfer (new customers)Mochi Health$639EstimatePrepaid in full3-month prepaid membership (membership covers 3 months)

High dose

MeasureSemaglutideabove 1.7 mg a weekTirzepatideabove 10 mg a week
Lowest with no commitmentmonth-to-month plansOrderlyMeds$447EstimateMonthly, pay per refillMochi Health$789EstimateMonthly membership
Lowest with a minimum termplans with a minimum number of months, billed monthlyGentle Health$597EstimateMonthly planOnly covered provider with this kind of plan at this dose.Gentle Health$807EstimateMonthly planOnly covered provider with this kind of plan at this dose.
Lowest if you prepayprepaid plansOrderlyMeds$373EstimateNew customers only2-month transfer (new customers)OrderlyMeds$748EstimateNew customers only2-month transfer (new customers)
Lowest with one all-inclusive feeone fee covers medication, care and shipping; no separate membershipOrderlyMeds$373EstimateNew customers only2-month transfer (new customers)OrderlyMeds$748EstimateNew customers only2-month transfer (new customers)
Lowest of any plan typeall plansOrderlyMeds$373EstimateNew customers only2-month transfer (new customers)OrderlyMeds$748EstimateNew customers only2-month transfer (new customers)

Common questions

What is the cheapest compounded semaglutide?

At a starting dose, the lowest listed all-in cost for the first 12 weeks is $298 at OrderlyMeds (2-month starter; estimate, new customers only). With no commitment, it is $417 at Mochi Health (monthly membership; estimate). Prices checked October 6, 2026; see the semaglutide comparison for every dose and plan. Full comparison →

What is the cheapest compounded tirzepatide?

At a starting dose, the lowest listed all-in cost for the first 12 weeks is $477 at Mochi Health (3-month prepaid membership; estimate, prepaid in full, membership covers 3 months). With no commitment, it is $507 at Mochi Health (monthly membership; estimate). Among plans with one all-inclusive fee, it is $507 at Gentle Health (monthly plan; estimate). Prices checked October 6, 2026; see the tirzepatide comparison for every dose and plan. Full comparison →

Which providers charge one all-inclusive fee?

DirectCare AI, Gentle Health, Henry Meds and OrderlyMeds list a single fee that covers the medication, clinician care and shipping, with no separate membership. The lowest such starting-dose figures are $298 at OrderlyMeds (2-month starter; estimate, new customers only) for semaglutide, and $507 at Gentle Health (monthly plan; estimate) for tirzepatide.

Do these prices include the membership?

Yes. Every 12-week figure includes all required charges. Mochi Health charges a membership and the medication separately, and both are added together here; the other providers charge one fee.

Which plans have no commitment?

DirectCare AI, Henry Meds, Mochi Health and OrderlyMeds offer month-to-month plans. Gentle Health requires a minimum number of months. Some plans are prepaid for several months; each plan's commitment is listed in the comparison tables.

Is compounded semaglutide or tirzepatide FDA-approved?

No. Compounded preparations are not FDA-approved and are not interchangeable with branded products such as Wegovy, Ozempic, Zepbound or Mounjaro.

How is the 12-week cost calculated?

It is the cash needed to stay on treatment for 12 weeks: three monthly charges for monthly plans, the full upfront payment for prepaid plans, and the program plus any refill needed for short programs. Promotions and checkout-only taxes are excluded, and figures that rest on an assumption are marked Estimate.

What this covers

Compounded semaglutide and tirzepatide injections from telehealth companies that Inside Telehealth profiles. Compounded preparations are not FDA-approved and are not interchangeable with branded products such as Wegovy, Ozempic, Zepbound or Mounjaro; see the GLP-1 access guide for branded options and the FDA's information on unapproved GLP-1 drugs. This is a price ordering, not a recommendation of a medication, dose or provider. Prices change often; confirm with the provider.